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Lado Okhotnikov, CEO of Meta Force gave an interview to Forbes France regarding new business areas

Cartel Blue, Inc

Forbes France has presented an article about new innovative projects of Meta Force company. Meta Force until now was known as a developer of the sophisticated DeFi platform and Neo Dao metaverse, with more than two million users, so work in biology and medicine was quite surprising. Lado Okhotnikov on holistic approach Meta Force head Lado Okhotnikov has been interviewed by Forbes France and said about business diversification and development of new areas. One of these areas is the production of organic cosmetics and dietary supplements, based on holistic principles. The holistic principle considers the human body as a unique Universe with an infinite number of interconnected objects. Drugs, dietary supplements, physical exercises should be applied taking into account both internal and external factors such as physiological, psychological, social ones. This approach dramatically increases the efficiency of dietary supplements or therapies and gives cosmetics special health-enhancing properties. Lado Okhotnikov announced a new cosmetics line called Holisthetic. Unique soaps, shampoos, balms, creams will come out into the market soon. DNA and Metaverses Meta Force proposed an innovative approach involving the use of DNA technologies in the metaverses. One of the basic elements of a metaverse is the user’s avatar, “traditional” avatars have limited customization options. Usually, it is the visual characteristics and a functional simulating physical characteristics such as strength, speed, endurance etc. Meta Force has developed technologies of digitalizing the user’s DNA data and has integrated it into the avatar. Thus, the avatar becomes a full-fledged “digital” clone. In this case, the user gets a unique simulator on which you can test drugs, diet, exercise etc. Avatar will help you to find the best drug, minimize side effects, and predict health trends. This approach corresponds as closely as possible to the principle declared by Meta Force: “Virtual meets real”. Lado Okhotnikov, CEO of Meta Force will tell you more about the projects in the article. Forbes’ Gala dinner Forbes France traditionally organizes a Gala dinner, inviting promising companies and interesting projects. They are given the opportunity to present their projects to guests, among them there are top businessmen, politicians, sports, cinema and show business stars. Forbes France Gala dinner in July 2024 was entirely dedicated to the Meta Force projects. About company Meta Force is a company that develops the well-known digital platform and the Neo Dao metaverse. By August 2024, the number of users was more than two million. Today, the company announced its entry into new business areas related to biology and medical research. Lado Okhotnikov is a head and Founder of the company. He is an expert in IT, cryptocurrencies and blockchain, investor, publicist and prominent polemicist who advocates the interests of the crypto community. Based on Dan Michael’s materials The head of Meta Force Press Center press@meta-force.space Contact Details Meta Force Press Center Dan Michael +1 786-814-1818 press@meta-force.space Company Website https://meta-force.space/

August 28, 2024 11:30 AM Eastern Daylight Time

Benchmark International Unveils the 2024 Global HVAC Industry Report

Benchmark International

Benchmark International, a leader in the mergers and acquisition (M&A) industry, is proud to announce the release of its 2024 Construction Spotlight: Global HVAC Industry Report. The comprehensive report provides valuable insights into the heating, ventilation, and air conditioning (HVAC) sector, examining the latest trends, challenges, and opportunities shaping the industry worldwide. The report underscores the pivotal role the HVAC industry plays in the construction sector, driven by advancements in technology, increasing demand for energy-efficient solutions, and evolving regulatory requirements. As construction activity remains strong across various regions, the demand for innovative HVAC systems continues to grow, positioning the sector for significant expansion in the coming years. Key findings from the report include: Market Expansion: The global HVAC industry is experiencing significant growth, fueled by rising demand for energy-efficient systems and increasing construction activities across various sectors. Technological Innovations: Advancements in HVAC technology, including smart HVAC systems, IoT integration, and AI-driven solutions, are transforming the industry and driving efficiency improvements. Regulatory Influence: Stringent environmental and energy efficiency regulations are shaping the HVAC industry, prompting companies to adopt more sustainable practices and innovative solutions. Benchmark International’s report serves as an essential resource for construction companies, HVAC manufacturers, investors, and other industry participants, offering strategic insights to navigate the evolving landscape and stay ahead of the competition. The report is now available on Benchmark International's website and is part of the firm’s ongoing efforts to provide comprehensive market intelligence to its clients. For more information and to access the full 2024 Global HVAC Industry Report, please visit https://www.benchmarkintl.com/insights/2024-construction-spotlight-global-hvac-industry-report/ ABOUT BENCHMARK INTERNATIONAL: Benchmark International is a global M&A firm that provides business owners with creative, value-maximizing solutions for growing and exiting their businesses. Benchmark International has handled over $11 billion in transaction value across various industries from offices across the world. With decades of M&A experience, Benchmark International’s transaction teams have assisted business owners with achieving their objectives and ensuring the continued growth of their businesses. The firm has also been named the Investment Banking Firm of the Year by The M&A Advisor and the Global M&A Network as well as the #1 Sell-side Exclusive Privately-held M&A Advisor in the World by Pitchbook and Refinitiv's Global League Tables. Contact Details Brittney Zoeller +1 813-898-2350 zoeller@benchmarkintl.com Company Website https://www.benchmarkintl.com/

August 28, 2024 09:35 AM Eastern Daylight Time

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How You Could Profit From The 2024 US Election With VantagePoint’s AI Software

Benzinga

By James Blacker, Benzinga U.S. stocks seem to be recovering following a recession scare in July that saw the S&P500 falling nearly 10% from its all-time high. The index has now risen almost 10% since the August 5 low, with the rebound partly driven by a series of economic reports this month on retail sales, inflation and producer prices, which have raised expectations that the Federal Reserve will cut interest rates later this year. However, with Vice President Kamala Harris set to square off against former president Donald Trump on November 5, analysts are warning that there could be more market turbulence yet to come, particularly with Harris leading in many polls after replacing President Joe Biden as the Democratic nominee. Election years typically bring volatility to global markets, and as election day looms, traders can expect to see intensifying fluctuations and shifts in investor sentiment. In fact, in a survey published by JPMorgan earlier this year, 20% of traders said they expected the election to be the biggest driver of stock movements this year. Why Elections Affect The Stock Market Presidential elections have wide-reaching ramifications for businesses and the economy, as they typically result in policy changes that can have a significant impact on various sectors. For instance, policy changes in healthcare can impact pharmaceutical stocks, while shifts in energy policy could affect oil and gas or renewables companies. Regulatory changes, fiscal policies, trade agreements and spending priorities can all be affected by election outcomes, creating both risks and opportunities for investors. Additionally, with so much uncertainty surrounding the future of the economy, global markets tend to be highly volatile as investors react to the latest polling data and presidential debates. This can potentially mean big price swings, making it crucial for traders to stay up to date with all the latest developments. During election periods, many traders tend to flock to commodities, indices and FX. In 2016, for example, after the UK’s referendum to leave the EU, the Germany Dax 40 index was the most traded instrument and the EUR-USD pair was the second most in demand instrument. How To Trade During Elections A golden rule for traders and investors is never to allow your own political views to inform your investing decisions. According to surveys conducted by the Pew Research Center, Democrat-aligned voters view the country’s economic condition as good under a Democratic president, while Republican-aligned voters rate the economy positively under a Republican president. This is despite the fact that average annual returns on the S&P500 were similar under both Obama and Trump, at 16.3% and 16%, respectively. Trading during an election year requires taking a strategic approach. With the right tools and strategies, investors can turn the heightened volatility into an opportunity to profit. Having access to reliable, real-time data and predictive analytics is crucial to making informed decisions. VantagePoint, a leader in A.I.-driven market forecasting software, can provide the insights needed to navigate the year of elections. Preparing For The 2024 Election With VantagePoint’s A.I. Software VantagePoint uses trained neural networks to provide traders with what it says are highly accurate, predictive forecasts of primary markets. These forecasts are based on intermarket analysis, meaning that the software compiles and analyzes data about the interconnectedness of global markets to detect hidden patterns that are undetectable by humans. Whereas traditional lagging indicators such as moving averages are simply a reaction to past price action, VantagePoint says its leading indicators can generate market predictions with up to 87.4% accuracy, and give you a head start on other traders. VantagePoint can also help you find exactly what to trade. There are thousands of securities to choose from, and it’s often the biggest decision you make as a trader. VantagePoint’s software helps you make asset selections, pinpointing the best stocks and options to trade. It even works with forex, crypto, futures and commodities. With VantagePoint's Intelliscan, you can quickly identify assets with a high potential to take off. The company says that this advanced scanning tool evaluates thousands of assets, highlighting the best stock and options opportunities. With clear, actionable insights, you can confidently target what to trade, armed with knowledge that helps you identify which stocks are likely to rise and which ones to avoid. This means you can potentially make smarter trades and maximize your time while minimizing effort. Traders and investors looking to get an edge in the markets during the election year could consider incorporating VantagePoint’s software into their trading strategies. With its A.I.-driven forecasts, traders can get a better understanding of future market movements and position themselves for success. VantagePoint is currently offering a free guide, called Electionomics 2024, which provides trading strategies that can maximize your profit during the election season using predictive artificial intelligence. For more information on VantagePoint, visit www.vantagepointsoftware.com. Featured photo by Tumisu from Pixabay. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains advertising content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

August 28, 2024 09:15 AM Eastern Daylight Time

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Atlas Lithium's Progress: Processing Plant Readies For Shipment To Site

Benzinga

By Mangeet Kaur Bouns, Benzinga Lithium exploration and development company Atlas Lithium Corporation (NASDAQ: ATLX) is making strides in its mission to begin environmentally sustainable lithium concentrate production. The company’s 100%-owned hard-rock lithium project, located in Brazil’s mineral-rich state of Minas Gerais, is nearing a critical milestone with the preparation of its modular dense media separation (DMS) lithium processing plant for shipment from South Africa to Brazil. The modular nature of the plant, a first of its kind for Brazil, embodies Atlas Lithium’s commitment to innovation and sustainability. As the company prepares for the final steps before the plant’s transcontinental journey, the broader implications for Brazil’s lithium industry and global lithium supply chains are becoming increasingly apparent. Pioneering Modular DMS Technology In Brazil Atlas Lithium’s decision to implement a modular DMS plant in Brazil marks a pioneering move in the country’s lithium industry. DMS technology, which uses a dense liquid medium to separate minerals based on their density, is a proven method in lithium processing. Atlas Lithium’s approach, however, optimizes this technology through a modular design that reduces both the physical and environmental footprint of the processing facility. This approach has several key advantages. The plant’s modular design simplifies transportation, installation and commissioning, allowing for a faster and more efficient setup compared to traditional processing plants. Additionally, the plant is designed to have the lowest water usage in the industry, a significant factor in regions where water conservation is critical. This focus on efficiency and sustainability not only potentially positions Atlas Lithium as a leader in responsible lithium production but may also set new standards for the industry as a whole. Strategic Preparation For The Plant's Transcontinental Journey Over the past few weeks, Atlas Lithium has been closely monitoring the final stages of the plant’s preparation in South Africa. Technical personnel from RTEKhave been on-site to ensure every component is ready for shipment. To date, 48 containers have been prepared, with the final count expected to exceed 100 before the plant begins its journey from the port of Durban, South Africa, to Santos, Brazil. The plant’s DMS modules have already undergone trial assembly in South Africa, ensuring that all components fit together seamlessly before disassembly and shipping. Among the final components being completed are the effluent systems, which have been upgraded for enhanced water efficiency, and the conveyors, which are integral to the plant’s operation. This meticulous attention to detail highlights Atlas Lithium’s commitment to delivering a plant that not only meets but exceeds industry standards. Brian Talbot, a principal at RTEK and a member of Atlas Lithium’s Operations Committee, emphasized the importance of this project during a recent inspection visit, stating, “Atlas Lithium’s modular plant represents a significant step for Brazil's lithium industry, and our direct involvement ensures that every detail is accounted for as we ship it to Brazil.” Scaling Up To Meet Surging Demand For Lithium And Other Key Metals Atlas Lithium’s broader strategy extends beyond the immediate goal of initiating lithium production. The company has significantly expanded its exploration portfolio in Brazil, now covering approximately 539 square kilometers or 133,294 acres. This potentially makes Atlas Lithium one of the key players in Brazil’s growing lithium sector, with extensive resources not only in lithium but also in other critical and battery metals such as nickel, rare earth elements, titanium, graphite and copper. This diverse portfolio helps further cement Atlas Lithium’s position as it aims to capitalize on the growing global demand for lithium, particularly in the U.S., where demand is expected to increase by nearly 500% by 2030, according to Fastmarkets. Lithium is a key component in a wide range of industries, including electric vehicles, renewable energy storage and consumer electronics, making Atlas Lithium’s efforts in Brazil a critical part of meeting this demand. Atlas Lithium's Strategic Positioning In The Global Lithium Market As the world transitions to greener energy sources, the demand for lithium and other critical minerals continues to rise. Atlas Lithium's initiatives in Brazil place it in a key position in this essential market. As the company prepares to ship its modular DMS plant to Brazil, the company’s strategic position within the global lithium market is becoming increasingly clear. With its extensive exploration portfolio, efficient lithium processing technology, and commitment to environmental and social sustainability, Atlas Lithium seems well-positioned to help meet the rising demand for lithium and other critical minerals. The company’s efforts not only promise to enhance Brazil’s role in the global lithium supply chain but also set a new benchmark for environmentally responsible mining practices. Featured Photo by MiningWatch Portugal on Unsplash. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

August 28, 2024 09:00 AM Eastern Daylight Time

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Liquid Death Becomes Official Partner of Brooklyn Football Club’s Women’s Franchise

Brooklyn Football Club

Liquid Death, the healthy beverage platform and one of the fastest-growing non-alcoholic brands, is now the official kit sponsor and water partner of Brooklyn Football Club (Brooklyn FC). The new Brooklyn Football Club kits will be on display at the inaugural opening day match for the women’s team against Carolina Ascent FC on Saturday, August 31, at 7:30 pm ET at Maimonides Park in Brooklyn, NY. “This is our first venture into professional US soccer, and we couldn’t be more thrilled to be on this journey with the Brooklyn Football Club women’s team,” said Ryan Heuser, Liquid Death’s senior vice president of experiential marketing. “We are excited to have our kit signage on display during the club’s season-opening match and to provide infinitely recyclable, ice-cold cans of Liquid Death to the passionate fans of Brooklyn.” As part of the agreement, fans will see Liquid Death at all Brooklyn FC concession stands, stadium signage, and special edition jerseys. Liquid Death will also collaborate on sideline ad boards and signage throughout the stadium, as well as joint events and co-promotions. Kits will be available for sale at the official Brooklyn FC online store. “The partnership between Brooklyn Football Club and Liquid Death is an important step both for our fast-growing clubs as well as for US soccer as a whole,” said Matt Rizzetta, President of Brooklyn Football Club and Chairman of North Sixth Group, principal owner and operator of the club. “Professional soccer in the US continues to attract the attention of the world’s most innovative brands, and we feel the marriage of Brooklyn Football Club and Liquid Death is a great example of this.” Liquid Death uses comedy and entertainment to promote both sustainability and healthy products. Liquid Death’s social following captures more than 9.8 million followers across TikTok and Instagram, making it the third most followed beverage brand globally. The company donates a portion of proceeds to nonprofits as part of its partnership with 5Gyres and the Thirst Project. For more information, visit www.brooklynfootballclub.com and follow the official social media channels of Brooklyn FC on Facebook, Instagram, and Twitter/X. About Brooklyn Football Club Brooklyn Football Club is a U.S. Soccer professional soccer club competing in USL Championship (U.S. Soccer second division men’s professional soccer), and in USL Super League (U.S. Soccer first division women’s professional soccer launching in August 2024). The two professional teams in Brooklyn are competing at the top of the USL footballing pyramid in the United States. About Liquid Death As one of the fastest growing non-alcoholic beverage brands, Liquid Death uses comedy and entertainment to make health and sustainability 50 times more fun. We take the healthiest things you can drink and package it into infinitely recyclable cans that compete with the fun marketing of unhealthy brands across energy drinks, beer, and junk food. Our product lines include mountain water, sparkling mountain water, sparkling flavored water, iced tea, and our hydration sticks, Death Dust. A portion of Liquid Death's proceeds goes to nonprofits who are helping fight plastic pollution and bring clean drinking water to those in need. For more information on Liquid Death please visit liquiddeath.com. Contact Details Brooklyn Football Club BKFC bkfc@n6krma.com

August 28, 2024 09:00 AM Eastern Daylight Time

Pasofino Gold: Unlocking Liberia’s Untapped Gold Potential

Benzinga

By James Blacker, Benzinga Liberia is rich in mineral resources. With gold, diamonds, and iron ore found in many parts of the country, the mining sector makes up a large part of its economy; revenues from iron ore accounted for almost half of Liberia’s earnings before 1990. Gold mining has historically been dominated by small-scale artisanal miners, but the last two decades have seen billions of dollars of investment pouring in from players such as ArcelorMittal (OTC:AMSYF), Liberty Gold (OTC:LGDTF) and Hummingbird Resources (OTC:HUMRF). These big players have paved the way for others like Pasofino Gold (OTC: EFRGF) to explore Liberia’s potential. The company sees Liberia as a strong candidate for gold mining due to its many unique characteristics, the extensive exploration performed by the company to date, their completed feasibility study and the positive economics resulting from that. Liberia, with a population of 5.3 million, stands as Africa's oldest modern republic. The government of Liberia has consistently shown a pro-mining stance, creating a favorable environment for mining activities. Since 2011, Liberia has been compliant with the Extractive Industries Transparency Initiative (EITI), becoming the first African country to adhere to its regulations. The country's mining laws are designed based on Australian mining regulations, providing stability and clarity for the industry. With a high level of Foreign Direct Investment (FDI) compared to GDP, Liberia stands as a potentially attractive investment destination in West Africa. With FDI surpassing $18 billion, Pasofino Gold considers Liberia an important gold exploration frontier. The Dugbe Gold Project The Dugbe Gold Project, which is owned by Pasofino, covers an area of 2,078 square kilometers (802 square miles) in southern Liberia, an area known for rich gold deposits. Bukon Jedeh is just one of 15 or more targets within the license. Only five of these targets have been drilled so far. Two of these became the Tuzon and Dugbe F deposits, which were initially discovered by Hummingbird in 2009 and 2011 respectively. Additionally, a number of opportunities have been identified to optimize the feasibility study, which was completed during the COVID-19 pandemic with challenges incurred during that time. Pasofino operates the project under a 25-year agreement with the government of Liberia, which includes a 3% royalty rate on gold production and a 25% income tax rate. The government holds a 10% interest in the project. Although less than 20% of the project has been explored so far, Pasofino Gold reports that the known discoveries are already promising. This includes the Dugbe F and Tuzon areas, which hold a combined Measured and Indicated Resource of approximately 3.3 million ounces of gold. Multiple drill-ready targets also display abundant gold mineralization at the surface, the company says. With such substantial resources, the Dugbe Gold Project is a key asset and holds great potential for future growth, Pasofino Gold argues, suggesting it may be on the verge of unlocking a significant gold resource in Liberia. The company has developed strong relationships with the people and community in the region, it says, and is excited about contributing to developing Liberia as a strong contender in the gold market. Featured photo by Shutterstock. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains advertising content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

August 28, 2024 08:55 AM Eastern Daylight Time

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Monogram Orthopedics (NASDAQ: MGRM) Lands Key Clinical Trial Partnership With India’s Leading Orthopedic Hospital Group To Advance Its Surgical Robot Tech

Benzinga

By Gerelyn Terzo, Benzinga The robotic orthopedics industry just took a step forward. Monogram Technologies (NASDAQ: MGRM), which is behind a futuristic surgical robot, has announced a strategic partnership with Shalby Limited (NSE: SHALBY), one of India’s leading orthopedic hospital groups. The venture adds to Monogram’s momentum as its latest technological breakthroughs proceed through the proper regulatory channels. As part of the collaboration, the companies will embark on a multicenter clinical trial campaign in which they demonstrate the safety and effectiveness of Monogram’s flagship mBȏs TKA System for robotic orthopedic surgery and implants. Monogram’s technology solution comprises over 750 precision parts, nearly two-dozen patent applications and 1.5 million-plus lines of code. Its robotics tech is deemed more advanced than that of legacy companies, and it is one of only a couple of autonomous players. Led by founder Vikram I. Shah, a world-renowned joint replacement surgeon, Shalby says it is the biggest orthopedic hospital chain on the planet. The company sits atop the rankings for arthroplasty based on volume, commanding 15% of India’s organized arthroplasty market share. With over a dozen hospitals sprinkled across 13 cities, Shalby seems uniquely positioned to capitalize on this market’s CAGR of about 20% amid India’s booming population of 1.4 billion people, the most populous nation in the world as of 2023, according to Pew Research. Monogram Technologies CEO Ben Sexson said of the collaboration, “With over 200,000 total knee arthroplasties (TKAs) annually, we believe India represents a massive market potential driven by a large population and demographic tailwinds. India is underpenetrated for robotics but is rapidly growing, and we believe the market potential is likely in the hundreds of systems.” Following the clinical trial, the partners will examine the post-trial transfer of Monogram’s robot to Shalby’s hospital system amid the potential for future collaborations. The trial will provide Monogram with access to Shalby’s network of seasoned knee replacement surgeons who are under the tutelage of Dr. Shah. Orthopedic Landscape Following a slowdown on the heels of the pandemic, orthopedic surgical volumes have been on the rise once again. In 2023, the global orthopedic surgery market expanded by 6.3% to $59 billion, outpacing its historical average. Research shows nearly 6 million lives are lost globally each year due to traumatic injuries, half of which could be preventable. However, legacy orthopedic surgery is in many ways inefficient and lacking in precision, with 88% of surgeries performed manually and most implants taking the form of one-size-fits-all, described as “one-size-fits-none” by some. While there are surgical robots in the industry, they are considered price-prohibitive and are quickly becoming obsolete. Monogram’s vision involves the use of one surgical robot to perform safe and quick orthopedic surgeries. When combined with best-fit implants, there is an expectation for better patient outcomes so desperately needed around the world. Through the partnership, Shalby will begin enrolling patients throughout India for surgeons to assess the success of Monogram’s mBȏs TKA System with the hospital group’s Consensus Knee System (CKS) implant, which is at a similar regulatory stage to Monogram’s mPress implants. On July 19th Monogram submitted it’s 510(k) application for mBôs TKA System Clearance. The application passed the Administrative Review and is under Substantive Review. According to MDUFA Performance Goals and Procedures, Fiscal Years 2023 through 2027, U.S. Food and Drug Administration, "For 510(k) submissions received in FY 2024, the average Total Time to Decision goal for FDA and industry is 124 calendar days.“ The company is pushing to conduct its first live inpatient OUS surgeries with Shalby pending regulatory approvals. Alignment Of Interests Shalby has seen continued growth, including a 20% 15-year CAGR in volume, with a footprint that covers eight countries and aggressive multi-continent international expansion plans. The company made its debut in the U.S. market several years ago when it acquired Sacramento, California-based Consensus Orthopedics. Shalby has set its sights on further expanding its footprint globally within the coming decade. “We believe many markets around the globe are completely underserved. We recognize the importance of advanced technologies to realize this ambitious goal,” stated Dr. Shah. Monogram’s Sexson shared how his company and Shalby are aligned in areas such as the caliber of surgeons and standard of care, while they are inspired by Shalby’s ambitious growth plans, including in the United States. Monogram intends to validate the value proposition of its mBȏs TKA System with real-world data, enabled by its recent regulatory submission coupled with a green light from its FDA Administrative Review, which Sexson describes as a “catalyst for strategic synergies” among the new partners. Investors who are interested in becoming a part of Monogram’s groundbreaking surgical robot technology as the company gears up to expand its reach globally can learn more about investment opportunities here. Read More About the Latest Developments At Monogram Orthopedics: Monogram Orthopedics (NASDAQ: MGRM) Aims To Overcome Robot Shortcomings With Its Advanced Solution Technology Is Enabling Remote Work In More And More Fields – Could Surgery Be Next? Surgical Robot Maker Monogram Orthopedics (NASDAQ: MGRM) Believes So AI In Orthopedic Surgery: How Leveraging AI Could Improve Surgical Outcomes Featured photo by GrumpyBeere on Pixabay. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

August 28, 2024 08:50 AM Eastern Daylight Time

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InMed Demonstrates Encouraging Data For Its Cannabinoid INM-089 In Treating Dry AMD, An Ocular Disease With Rising Patient Numbers As National Population Ages

Benzinga

By Meg Flippin, Benzinga When it comes to diseases of the eyes, age-related macular degeneration or AMD is a big one, afflicting 19.8 million people or 12.6% of Americans aged 40 and older. In adults 50+ it is the most common cause of severe loss of eyesight. People suffering from AMD, which affects central vision, lose the ability to see fine details. As the disease progresses, sufferers may not be able to see faces, read small print and even drive. What makes this incurable disease even worse is that in the early stages, there can often be no initial signs or symptoms. Left unchecked, patients may lose central field vision in the affected eye within 24 months of disease onset. While treatments are available, most focus on controlling the symptoms rather than addressing the underlying causes. Moreover, the treatments often rely on patients making changes to their lifestyles such as eating healthy and quitting smoking, which isn’t always easy to do. Cannabinoids May Be Part Of The Answer InMed Pharmaceuticals Inc. (NASDAQ: INM), a leader in cannabinoids and cannabinoid analogs pharmaceutical research, development, manufacturing and commercialization, may have a solution with INM-089, the company’s ocular program for AMD, which it launched in November. With scientific research continually pointing to the neuroprotective effects of cannabinoids, InMed set out to develop a cannabinoid analog that could treat ocular diseases such as AMD. For those with AMD, neuroprotection is essential to preserve the nerve cells in the eyes and potentially slow or reverse eye damage, which InMed says it is in the process of proving INM-089 can do. Studies of InMed’s INM-089 cannabinoid analog, which is a small molecule compound, demonstrated its ability to proactively protect the nerve cells in the back of the eye in the retinal area, exhibiting its therapeutic potential for AMD. Small molecules can cross the blood-brain barrier and are typically better suited for multiple drug delivery options because they can be efficiently absorbed, making INM-089 a promising drug candidate for pharmaceutical use, reports InMed. Studies Demonstrate INM-089’s Benefits The company has data to back up its assessment. Results from several in vitro and in vivo studies showed INM-089 provides neuroprotection of photoreceptors and improves photoreceptor function, enhances the integrity of the retinal pigment epithelium (RPE), preserves retinal function in the back of the eye and improves the thickness of the outer nuclear layer of the retina where photoreceptors are located. Neuroprotection in AMD remains an unmet medical need and a new treatment option addressing neuroprotection may help to eliminate or reduce the effects of the condition, InMed says. More recently, InMed found in a proof of concept study that INM-089 may be more effective in treating dry AMD than wet AMD and may be an “important” candidate for Geographic Atrophy (GA) which is common in more advanced cases of dry AMD, affecting the center of the macula. In vivo preclinical studies in AMD disease models demonstrated all of the previous benefits, as well as a reduction in extracellular autofluorescent deposits, a hallmark of dry AMD, the company reports. The latter wasn’t demonstrated in previous trials, leading InMed to believe INM-089 is ideally suited for dry AMD. Dry AMD Needs Immediate Attention Among forms of AMD, dry AMD is the most common, accounting for 85% to 90% of all cases. In 2023, the U.S. had the highest prevalence of dry AMD. With dry AMD, waste proteins and lipids begin to accumulate due to poor circulation and poor waste flushing in the eye. The advanced stage of dry AMD is referred to as Geographic Atrophy, with approximately five million patients globally suffering from it. The prevalence of GA is projected to continue to rise in the coming years, with an estimated 18.5 million cases globally by 2040 as the population ages. “We are very excited with the data from recent preclinical studies demonstrating both significant functional and pathological improvements from INM-089 in the AMD model,” Dr. Eric Hsu, SVP of preclinical research and development at InMed said. “While a few treatment options are currently available, their efficacy is limited and may be associated with several undesirable side effects. We see an opportunity for INM-089 to slow the progression and to fill a significant gap in the treatment of this chronic disease.” Taking It To The Next Level Given all the positive results of its studies, InMed said it recently engaged a Contract Development and Manufacturing Organization (CDMO) to assist in scale-up manufacturing process development of the active pharmaceutical ingredient. Meanwhile, the company is internally developing drug product formulation to support the next stages of development activities. What’s more, additional preclinical activities are ongoing to further understand the mechanism of action including receptor interactions and drug metabolism and pharmacokinetics studies, InMed said. All of these are being conducted with the goal of eventual commercialization of INM-089. The global population is aging, which means cases of AMD are poised to increase. That’s bad news given there is no cure, and the effects of this disease can be debilitating and life-altering. InMed doesn’t want that to be the case, and is betting its cannabinoid can play an important role in finding better treatments for AMD. With positive results from several studies under its belt, InMed is one step closer to bringing INM-089 to the millions of older adults who suffer from this disease. Featured photo by Jeremy Wong on Unsplash. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

August 28, 2024 08:40 AM Eastern Daylight Time

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Loserball.com announces Launch of Unique Fantasy Football Game for Casual Fans

Loserball

Loserball.com, a new fantasy football game that has taken an opposite approach by allowing users to win based on losing, launched its brand-new app through the Apple Store, Google Play, and on the web debuting a unique and fun way to enjoy professional football games. Understanding the power of strategic partnerships, Loserball.com immediately tapped industry-leading production house, Better Sports Network, to create content and promote through their iconic brand FantasyAlarm.com. Loserball threads the needle between casual fans and dedicated fantasy players by simplifying the game to selecting just three (3) NFL teams each week. Using sixteen (16) categories of futility, from fumbles to incomplete passes, Loserball.com makes every play worth watching. Ultimately, this contrarian approach to fantasy football will create a true paradigm shift in how people watch and enjoy NFL games beginning this season. Better Sports Network brings a powerhouse of resources and talent to cover the game from this opposite angle. With drive time radio on SiriusXM, over 450 content creators and a production staff that delivers written, audio, video and live-streaming content for hundreds of thousands of fantasy football players, BSN is ready to deliver content following this unique concept. "Fantasy Alarm is the ultimate destination for all things fantasy, including Loserball’s wacky, yet innovative approach to the game. We couldn’t sit on the sidelines,” said Matt Deutsch, Co-Founder of Bettor Sports Network. "We're hooked on their vision of fumbles over field goals and penalties over points and look forward to entertaining NFL fans with this totally new approach to the sport we love." "We are proud to deliver this unusual game concept so fantasy football players can now truly enjoy every play - whether it is a touchdown or a fumble," said Jonathan Gruber, Founding Loser. “Attaching ourselves to the leading private brand in the fantasy content space made sense and with the parent company’s production capabilities, we can entertain and inform all season long.” With this partnership, Loserball.com and Bettor Sports Network are set to popularize this new concept together, and equally as important, entertain NFL fans in a unique way. As the excitement starts to build for a season of gaffes, goofs, and gridiron guffaws, Loserball will be there to start a new mantra, "May the Worst Team Win!" To sign up and start playing today, visit app.loserball.com/signup. To learn more about Bettor Sports Productions, visit BettorSportsProductions.com. To dominate your fantasy leagues and daily fantasy sports play, visit FantasyAlarm.com. About Loserball.com Loserball began with humble roots, with Gruber rooting for teams to lose for decades. In June of 2023, Loserball won the Fantasy Sports and Gaming Association's Elevator Pitch Award, and has since garnered top fantasy advisors such as Fantasy Hall of Famer Rick Wolf and Hot Paper Lantern's Ed Moed to join the fun. This year will have free-to-play games for anyone that wants to create or join a league, in addition to select prizes. In 2025, Loserball will add DFS-style player games for the NFL season. About FantasyAlarm.com FantasyAlarm.com, a wholly owned subsidiary of Bettor Sports, LLC, is the premier one-stop-shop for both seasonal and daily fantasy sports players. Fantasy Alarm features best-in-class content, personalization, and interactivity. Our commitment to quality has won us many industry awards, including Best Mobile App, Best Daily Fantasy Sports Tool & Content, Most Innovative Fantasy Product, and Best Radio Show. Fantasy Alarm has partnerships with SiriusXM, Sporting News, The New York Post, and many others in sports, solidifying its leadership position in the $7B fantasy sports industry. In addition to FantasyAlarm.com, we also own Wager Alarm, a full-featured website for sports bettors, and FantasyRundown.com, the largest content aggregator in the fantasy sports space. Both properties share the same dedication to quality and top-notch service that makes Fantasy Alarm a leader in the fantasy sports industry. Bettor Sports Productions is a leader in creating and distributing high-quality sports content, specializing in video production, social media management, and live event streaming. Our production arm provides best-in-class production and marketing services to some of the largest brands in sports entertainment, including FFPC, Warren Sharp Sports, MGM, Underdog Fantasy, and many more. We are dedicated to enhancing brand engagement and expanding audience reach for top sports entertainment companies. Contact Details Jonathan Gruber +1 415-902-9336 jonathan@loserball.com Company Website http://Loserball.com

August 28, 2024 08:03 AM Eastern Daylight Time

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